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Broccoli Sprouts There have been at least 300 published studies made on the benefits of the SGS found in broccoli sprouts. Below, are some samples. Please note that while this list is not comprehensive, it is clearly indicative of the interest there is in studying broccoli sprouts and the potential benefits they have to offer. Jed W. Fahey, Yuesheng Zhang, and Paul Talalay Broccoli Sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens Proc. Natl. Acad. Sci. USA, Vol. 94, pp. 10367-10372, September 16, 1997. N.-A. Pham, J. W. Jacobberger, A. D. Schimmer, P. Cao, M. Gronda, and D. W. Hedley The dietary isothiocyanate sulforaphane targets pathways of apoptosis, cell cycle arrest, and oxidative stress in human pancreatic cancer cells and inhibits tumor growth in severe combined immunodeficient mice Mol. Cancer Ther., October 1, 2004; 3(10): 1239 - 1248. A. V. Singh, D. Xiao, K. L. Lew, R. Dhir, and S. V. Singh Sulforaphane induces caspase-mediated apoptosis in cultured PC-3 human prostate cancer cells and retards growth of PC-3 xenografts in vivo Carcinogenesis, January 1, 2004; 25(1): 83 - 90. M. L. Kerns, D. DePianto, A. T. Dinkova-Kostova, P. Talalay, and P. A. Coulombe Reprogramming of keratin biosynthesis by sulforaphane restores skin integrity in epidermolysis bullosa simplex PNAS, September 4, 2007; 104(36): 14460 - 14465. M. Tanito, H. Masutani, Y.-C. Kim, M. Nishikawa, A. Ohira, and J. Yodoi Sulforaphane Induces Thioredoxin through the Antioxidant-Responsive Element and Attenuates Retinal Light Damage in Mice Invest. Ophthalmol. Vis. Sci., March 1, 2005; 46(3): 979 - 987. Mark V. Galan, M.D., Arfana A. Kishan, M.D., Ann L. Silverman, M.D.*. William Beaumont Hospital, Royal Oak, MI. Broccoli sprouts may eradicate H pylori infection [a primary cause of stomach ulcers and stomach cancers] The American Journal of Gastroenterology Volume 98, Issue 9, Supplement 1 , September 2003, Page S57 P. Thejass and Girija Kuttan Department of Immunology, Amala Cancer Research Centre, Amala Nagar, Thrissur, Kerala State 680555, India Antimetastatic activity of Sulforaphane Life Sciences Volume 78, Issue 26, 22 May 2006, Pages 3043-3050 "Nrf2 activation by sulforaphane restores the age-related decrease of TH1 immunity: Role of dendritic cells" Authors: H.-J. Kim, B. Barajas, M. Wang, A.E. Nel Reverses aging mechanisms in immune system Journal of Allergy and Clinical Immunology (Elsevier) Published online ahead of print 5 March 2008, doi:10.1016/j.jaci.2008.01.016
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